Ramos-Vinolas was soon back in the match, though, holding in the second set and breaking Murray in the third and seventh games to pave the way for a decider.
Zverev was in trouble when a poor serve and volley was followed by a forehand into the net that gifted Nadal the first break, before excellent work at the net quickly brought up a double-break 5-1 advantage. "When you play against a player that wants to hits every ball, sometimes you are in his hands".
"It was a tough first match", Murray told Sky Sports.
In another match, Nadal dropped a set in the second round against Kyle Edmund but was ruthless as he dispatched another young gun, the 20-year-old Zverev who was reduced to trashing rackets in frustration against the Spaniard. "It was just in a very awkward moment to give me a warning", Djokovic said.
"It has been a hard year for me because I know what it takes to get right up to the top and have the consistent results you need".
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He reached the final of his first tournament, Doha, where Djokovic ended Murray's career-high 28-match winning streak.
Nadal, the nine-time French Open champion, looks to be getting things together on his preferred surface too.
But the 29-year-old Spaniard hit back to win the the second set by the same score.
"It's good I'm able to play like that. I'm confident that with dedication and commitment and a positive mindset, I can get to the level where I want to be".
"I m playing much better with my forehand". I was close, I think.
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Murray looked a bit sluggish early on against Muller, dropping serve in the opening game.
But Goffin broke him in the eighth game and held firm on his own serve when taken to deuce in a tight 11th game.
On a side note, Murray's father-in-law Nigel Sears, who collapsed at the Australian Open past year, will be running a marathon Sunday. He set up a match point with an excellent backhand cross-court victor as he retrieved a shot deep into the court, and clinched victory when Muller hit a forehand wide.
He managed to take six consecutive points to re-establish the lead but he was powerless from stopping the resurgent Ramos-Vinolas from sealing the next three games to secure a quarter-final berth against fifth-seed Marin Cilic.
Third seed Stan Wawrinka beat Czech Jiri Vesely 6-2 4-6 6-2 while sixth seed Dominic Thiem of Austria lost only four first service points as he beat Robin Haase 6-3 6-2 to set up a meeting with Belgian 10th seed David Goffin.
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TheStreet downgraded Rice Midstream Partners from a "b-" rating to a "c+" rating in a research note on Thursday, February 2nd. Three research analysts have rated the stock with a hold rating and six have assigned a buy rating to the company.
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