Mr Makin said he did not think Brady had any information which would help the search for Keith Bennett, the only victim of Brady and Hindley whose remains have never been found.
But Ian Brady's fascination with Nazism and sexual perversion would take hold of his younger lover Myra Hindley as they plotted and carried out the abduction, torture and murders of children.
"We can confirm a 79-year-old patient in long-term care at Ashworth High Secure Hospital has died after becoming physically unwell".
His lawyers said he had emphysema and was terminally ill.
Brady and his lover accomplice Myra Hindley shocked Britain in the 1960s for the way they lured young children, tortured and killed them, and buried their bodies on a remote moorland on the outskirts of Manchester.
Four of the victims were buried on Saddleworth Moor, east of Manchester, and their bodies remained there for decades.
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Hindley and Brady were caught after involving Hindley's brother-in-law David Smith in the murder of Edward Evans in October 1965.
They include medical reports from a consultant psychiatrist concerning Brady's mental health, the attending doctors at time of death, the palliative care staff, his medical notes and an expert report regarding feeding through a tube in the nose.
In February this year, he was refused permission for another court bid to be transferred to prison. She died never having found her son Keith and always believed Brady could provide details that would have identified where his body was buried.
Robin Makin, who is the executor of Brady's will, said he was called to go and see him just hours before his death.
"It's been years and years of anguish and pain for us and the families of the victims", Terry Kilbride, 62, told The Sun.
The trial judge, Mr Justice Fenton Atkinson, described Brady and Hindley in his closing remarks as "two sadistic killers of the utmost depravity".
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The senior coroner for Sefton, Christopher Sumner, said he would not authorise the release of Brady's body until he had been assured that the ashes would not be scattered on Saddleworth Moor. "I think that if he had been able to assist in its location it would have happened in the 1980s". "That has to come from him".
The police, however, want to consider all the potential as a result of which Brady wrote a letter indicating where the corpse is located and which he ordered to be opened after his death.
The youngster's mother Winnie Johnson died never knowing.
He said they discussed Brady's legal wishes and arrangements for his funeral, which he said he could not make public presently but added "in due course these will become available".
He told ITV News it was "going to feel good" to see the murderer dead, in an interview recorded on Monday before Brady's death was announced.
Their first victim was 16-year old Pauline Reade, who was murdered after Hindley asked her to help find her glove lost on Saddleworth Moor.
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Imprisoned since 1966, Brady was given three life sentences for the killings of Downey, Evans, and Kilbride and later went on to admit murdering Bennett and Reade, but was never tried in court for their deaths.
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