Nicolas Otamendi was free in the box to head home a fourth from David Silva's cross - City's crossing was absolutely flawless at times and it certainly could have been more than 6-0 given their dominance and ruthlessness going forward.
Guardiola has been full of praise for Belgium global De Bruyne, who he described as "one of the best players I've ever seen in my life" after the 4-0 Champions League victory over Feyenoord on Wednesday.
The match was over after the first half, as City went into the interval 3-nil up.
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It wasn't pretty - especially on offense - but they did enough to get the win, so that is enough to earn them some decent grades. Over on the Bengals' side, they're now 0-1 as well after their 20-0 shutout defeat at the hands of the Ravens .
The Hornets set to play against to the team who is now at the second position, Man City. "But he's a guy I encourage to play, not just to score goals. But in other games we will have to find another way to win".
With this result, City has now scored 17 goals unanswered across all competitions, as part of four consecutive victories.
Smiling, De Bruyne, 26, added: "Sergio's not the only one who doesn't get the recognition he deserves".
"Listen I always think he works hard", said Guardiola, of Aguero. "So if you tell me that I will do as well as he has done I will be happy of course".
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There's been a healthy amount of debate what is actually the Major League Baseball record for longest winning streak. But after a walk to load the bases, the Royals got both Bruce and Carlos Santana to pop out in foul territory.
Even Philippe Coutinho's first start could not secure the points for Liverpool, who trailed to a Scott Arfield goal before Mohamed Salah equalised with his fifth of the season.
It was a grim afternoon for Watford, and one they'll want to forget immediately.
The summer transfer window was one the craziest we have ever seen.
On their travels in the league so far this season, City have been flawless.
China's biggest bitcoin exchange to halt trading
Bitcoin tumbled immediately after Chinese bitcoin exchange BTCChina announced that it will stop all trading from September 30. Founded in June 2011, Bitcoin China was the first Bitcoin transaction platform in China and is now the first to be shut down.
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