While the Pentagon stressed the narrow, precise-nature of the attacks, Trump emphasized in announcing the strikes that the allied forces "are prepared to sustain this response until the Syrian regime stops its use of prohibited chemical agents".
Assad's allies, including Iran and Lebanon's Hezbollah group, also condemned the strikes.
Dunford said there was some "activity" by Syrian surface-to-air missiles, but there were no reports of USA or allied casualties.
This means jets could strike without having to fly over Syria and avoid anti-aircraft defenses.
Syria agreed to give up its chemical weapons arsenal in 2013 and submit to OPCW inspections.
Now, Trump has abruptly deepened U.S. involvement in Syria, mustering a coalition of U.S., French and British forces to attack Syrian facilities related to production of chemical weapons after a poison gas attack last week killed dozens of people in Douma, Syria.
It added: "In these circumstances, the global community can not remain inactive and should take all necessary measures to prevent such attacks from being repeated in the future, especially against [a] defenseless civilian population".
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Mattis described them as a "one-time shot" to send a strong message to Assad not to use chemical weapons again.
Trump promised that the strikes wouldn't necessarily be a one-off.
"The nations of Britain, France, and the United States of America have marshalled their righteous power against barbarism and brutality", US President Donald Trump said in an address from the White House at about 21:00 local time (02:00 BST).
"The aggression is a flagrant violation of worldwide law, a breach of the global community's will, and it is doomed to fail", said state news agency SANA.
Trump announced from the White House on Friday night that the U.S., in coordination with France and the United Kingdom, had launched strikes on Syria following a week of threats of retaliation for an alleged chemical weapons attack on civilians by the regime of Syrian President Bashar al-Assad.
The French President Emmanuel Macron said the strikes had been limited to Syria's chemical weapons facilities despite reports from pro-Assad commanders of attacks on other targets in the country.
Freeland did not specify how she knew that the Syrian government was responsible, though she said Canada is working with non-governmental organizations and others to collect evidence of war crimes and other atrocities in Syria.
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The departure of US troops, military strategists say, will likely pave the way for Assad's consolidation of control in the country, backed by Russia, Iran and the Lebanese militia Hezbollah.
Questioning on if it was right to back strikes without giving the legislature a say, as recent Prime Ministers have done, Mrs.
"A combined operation with the armed forces of France and the United Kingdom is now underway".
Syria has denied using chemical weapons.
"We were very precise and proportionate, but at the same time, it was a heavy strike", he said. "I have zero confidence that we could control where that goes then".
Intelligence and open source accounts indicated that the Syrian government was behind the attack on Saturday, according to the PM.
A senior official in a pro-Assad regional alliance told Reuters that "all military bases were evacuated a few days ago" after an early warning from Russian Federation about the strikes.
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